Radiation wounds are difficult to treat. There is considerable evidence of the beneficial effects of HBO on radiation necrosis and has become a useful adjunct to surgery. Among the bony structures, the effect on osteoradionecrosis of the mandible is crucial. Among the soft tissue, the effect is impressive.

Without Hypberbaric Oxygen - HBO, treatment often requires radical surgical intervention, which can lead to complications. Hyperbaric Oxygen Therapy is recommended for delayed radiation injuries for soft tissue and bony injuries of most sites.